Rhodium-catalysed enantioselective synthesis of 4-arylchroman-2-ones
نویسندگان
چکیده
منابع مشابه
Enantioselective rhodium-catalysed 1,4-additions of 2-heteroarylzinc donors using Me-DUPHOS.
The enantioselective 1,4-addition of 2-(substituted)thienylzinc and 2-furanylzinc reagents has been achieved (up to 99 : 1 er) using a complex derived from [Rh(C(2)H(4))(2)Cl](2) and Me-DUPHOS.
متن کاملTriphenylphosphine Catalysed Facile Multicomponent Synthesis of 2-Amino-3-Cyano-6-Methyl-4-Aryl-4H-Pyrans
Triphenyl phosphine(PPh3), an efficient and reusable catalyst, catalysed the synthesis of 2-amino-3-cyano-6-methyl-4-aryl-4H-pyran-5-ethylcarboxylate derivatives by one-pot condensation of aromatic aldehydes, malononitrile and ethyl acetoacetate in EtOH-H2O (1:1) at reflux conditions. The results show that ...
متن کاملSYNTHESIS OF 3-ARYLMETHYL-4- THIAZOLIDINE-CARBOXYLIC ACID-2-ONES AND 2-THIONES
Barium salts of dibenzylidene cystines 8a-c were obtained from the reaction of Lcystine with benzaldehyde or its derivatives in the presence of barium hydroxide. Their reduction with zinc and hydrochloric acid in methanol yielded the Narylmethylcysteines ?9a-c?. These can, in turn, be converted by esterification into the methyl esters ?10 a-c. ?Reaction of N, N'-carbonyl diimidazole (Im C...
متن کاملA convergent rhodium-catalysed asymmetric synthesis of tetrahydroquinolines.
Rh-catalysed conjugate additions of 2-aminophenyl boronic acid derivatives were exploited in diastereoselective and asymmetric syntheses of tetrahydroquinolines. In both cases, combinatorial variation of the substitution of the tetrahydroquinoline ring system was possible.
متن کاملEnantioselective synthesis of beta2-amino acids using rhodium-catalyzed hydrogenation.
A series of protected beta2-dehydroamino acids has been prepared in three steps from commercially available starting materials in good yields. These were used as substrates in rhodium-catalyzed asymmetric hydrogenation applying a mixed ligand system of monodentate phosphoramidites and phosphines. Optimization of the catalyst structure was achieved by high throughput experimentation. High enanti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Org. Biomol. Chem.
سال: 2012
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c1ob06586f